Bronchial obstruction due to respiratory mucosal sloughing in toxic epidermal necrolysis.
نویسندگان
چکیده
A 17 year old woman is described who nearly asphyxiated because of sloughing of the bronchial mucosa as a result of toxic epidermal necrolysis. Bronchoscopic aspiration of bronchial slough proved life saving.
منابع مشابه
Toxic epidermal necrolysis following treatment of pseudotumour cerebri: a case report
Toxic Epidermal Necrolysis and Steven-Johnson syndrome are entities on a spectrum of cutaneous reactions that usually occur as an idiosyncratic reaction to certain drugs. The distinction between TEN and SJS is based on the percentage of skin involved with SJS being less than 10% and TEN being more than 30%. They exhibit severe skin blistering and sloughing with mucosal involvement and can be fa...
متن کاملToxic epidermal necrolysis and Stevens-Johnson syndrome: a review.
OBJECTIVES The aims of this review are to summarize the definitions, causes, and clinical course as well as the current understanding of the genetic background, mechanism of disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson syndrome. DATA SOURCES PubMed was searched using the terms toxic epidermal necrolysis, Stevens-Johnson syndrome, drug toxicity, drug interaction, and ...
متن کاملFatal case of cephalexin-induced toxic epidermal necrolysis
PURPOSE To describe a case of toxic epidermal necrolysis likely caused by cephalexin with a review of the literature. CASE An 80-year-old male with a known allergy to cephalosporins, residing at a long-term acute care hospital, received cephalexin for a urinary tract infection. And 1 day after starting therapy, the patient developed an extensive erythematous rash accompanied by skin sloughing...
متن کاملToxic epidermal necrolysis. A case report.
We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.
متن کاملExtracorporeal membrane oxygenation in a patient with refractory acute respiratory distress syndrome secondary to toxic epidermal necrolysis.
Toxic epidermal necrolysis (TEN) is a rare condition affecting an estimated 1 to 2 cases per million per year, with reported mortality between 30% and 50% typically because of multiorgan failure or sepsis. 1 Acute pulmonary complications from this disorder include bronchial mucosal sloughing, pulmonary edema, and infectious pneumonitis. Pulmonary complications in TEN occurred in 46% of patients...
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ورودعنوان ژورنال:
- Thorax
دوره 49 9 شماره
صفحات -
تاریخ انتشار 1994